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Vitamin B12 injections are most clinically appropriate in cases of confirmed vitamin B12 deficiency, malabsorption syndromes including pernicious anaemia or post-gastric surgery, significant symptoms where rapid restoration of vitamin B12 levels is required, or failure of oral supplementation due to poor absorption
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Local infections, temporomandibular disorders, surgery, radiotherapy in the head and neck, neoplastic processes, as well as connective tissue disorders (such as lupus erythematosus) can cause chronic trismus [7]